Band 8a Proteomic Facility Lead | Royal Free London NHS Foundation Trust
| Posting date: | 09 June 2025 |
|---|---|
| Salary: | Not specified |
| Additional salary information: | £61,927 - £68,676 per annum inclusive of London HCAS |
| Hours: | Full time |
| Closing date: | 09 July 2025 |
| Location: | London, NW3 2QG |
| Company: | Royal Free London NHS Foundation Trust |
| Job type: | Permanent |
| Job reference: | 7218695/391-RFL-7218695 |
Summary
We are looking for an excellent candidate with expertise in mass spectrometry to lead our NHS UKAS-accredited diagnostic proteomics facility of the Jack O’Neill Laboratory, (JONAL).
The post-holder will work with the clinical teams under the direction of the Head of Fibril Typing and laboratory director, providing scientific and technical support to contribute to the overall activities of the Centre. They will lead and have responsibility for the supervision and training of staff and users in the daily management of the mass spectrometry facility, recruitment of new staff, sourcing and investigating options and responsibility for the purchase of equipment, with full consideration for the cost effectiveness of different solutions. They will have to develop and validate new and novel methods with mass spectrometry in line research advances.
The Proteomic Lead will be responsible to lead to provide a clinical diagnostic service and running the diagnostic proteomic facility.
They will be responsible the daily management and laboratory activities of the proteomics facility, training / supervising staff reporting to the Head of the Fibril Typing. Producing formal reports of service output, conduct audits, attend weekly diagnostic MDT’s, being responsible for generating formal electronic reports of diagnostic proteomic results.
They will maintain proteomic laboratory accreditation, including EQA schemes, under the direction of the head of fibril typing and quality manager for the Jack O’Neill laboratory.
They will be expected to keep abreast of developments, techniques and approaches in the field of Mass Spectrometry, proteomics and bioinformatics, including new analytical tools and instruments. They will revise, validate, and implement protocols and procedures to improve diagnosis, ensuring use of the most accurate up to date diagnostic testing for optimum patient care in the delivery of high quality care, clinical governance and patient safety.
They will be required to maintain and develop collaborations at national and international level. The post holder will have an opportunity to support cutting-edge proteomics research both within the Centre and with external collaborators, including clinicians and scientists both nationally and internationally.
The NHS National Amyloidosis Centre (NAC), based at the Royal Free Hospital in London, is the only centre in the UK and one of the few centres worldwide specialising in amyloidosis. It provides a comprehensive UKAS-accredited diagnostic service for the national caseload of amyloidosis patients as well as management advice and delivery of high-cost amyloid-specific therapies.
The Jack O’Neill Laboratory (JONAL) is a highly specialised laboratory which has developed dedicated methodology for the diagnosis of amyloidosis and systemic autoinflammatory diseases and is central to the NHS England-funded national highly specialised services based at the NAC. The JONAL consists of a specialised team covering specimen reception, molecular genetics, histopathology and proteomics.
Proteomics has become central to the accurate diagnosis and typing of amyloidosis and is used routinely within the Centre. The Centre continues to research and validate novel proteomic techniques for clinical diagnostic purposes as well as pursing basic science proteomic research.
Please see attached job description for more information about this role and working at Royal Free London NHS Foundation Trust.
This advert closes on Monday 23 Jun 2025