13443- Postdoctoral Research Assistant
| Dyddiad hysbysebu: | 28 Tachwedd 2025 |
|---|---|
| Cyflog: | £41,064 i £48,822 bob blwyddyn |
| Oriau: | Llawn Amser |
| Dyddiad cau: | 12 Rhagfyr 2025 |
| Lleoliad: | Edinburgh, Scotland |
| Gweithio o bell: | Ar y safle yn unig |
| Cwmni: | University of Edinburgh |
| Math o swydd: | Dros dro |
| Cyfeirnod swydd: | 13443 |
Crynodeb
Grade UE07: £41,064- £48,822 per annum
CMVM- Centre for Cancer Research, School of Genetics and Cancer
Full Time: 35 hours per week
Fixed Term: 12 months
The Opportunity:
We are looking for a Post-Doctoral Research Assistant to join our team based at IGC (ECRC) for a one year post. Our lab studies mutations in the metabolic isocitrate dehydrogenase (IDH1/2) genes and this project focusses on how these mutations re-program liver cells, in the context of biliary cancer. We are using CRISPR-edited human cells and novel transgenic models in mice to examine how these mutations affect the liver’s response to damage and explore the link between injury and metabolic re-programming.
Ideally, the post holder should have experience of animal work, cell culture, tissue processing and will be able to perform laboratory analyses of human and mouse tissue including genotyping, IHC, rt-PCR, western blotting and prepare samples for external providers (transcriptomics, metabolomics). A large proportion of the work will be based on animal experiments; a PIL is a desired but not an essential requirement for the post. Experience of in vivo models of liver cancer and/or liver disease would be highly desirable.
This post is full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.
The salary for this post is £41,064 to £48,822 per annum.
Your skills and attributes for success:
A proactive, enthusiastic approach to science
Ability to work both independently and as part of a team
Experience of molecular techniques that may include (but not limited to) rt-PCR, IHC, genotyping and sample preparation for external providers
Experience of tissue processing and cell culture
CMVM- Centre for Cancer Research, School of Genetics and Cancer
Full Time: 35 hours per week
Fixed Term: 12 months
The Opportunity:
We are looking for a Post-Doctoral Research Assistant to join our team based at IGC (ECRC) for a one year post. Our lab studies mutations in the metabolic isocitrate dehydrogenase (IDH1/2) genes and this project focusses on how these mutations re-program liver cells, in the context of biliary cancer. We are using CRISPR-edited human cells and novel transgenic models in mice to examine how these mutations affect the liver’s response to damage and explore the link between injury and metabolic re-programming.
Ideally, the post holder should have experience of animal work, cell culture, tissue processing and will be able to perform laboratory analyses of human and mouse tissue including genotyping, IHC, rt-PCR, western blotting and prepare samples for external providers (transcriptomics, metabolomics). A large proportion of the work will be based on animal experiments; a PIL is a desired but not an essential requirement for the post. Experience of in vivo models of liver cancer and/or liver disease would be highly desirable.
This post is full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.
The salary for this post is £41,064 to £48,822 per annum.
Your skills and attributes for success:
A proactive, enthusiastic approach to science
Ability to work both independently and as part of a team
Experience of molecular techniques that may include (but not limited to) rt-PCR, IHC, genotyping and sample preparation for external providers
Experience of tissue processing and cell culture