Dewislen

Senior Molecular Biologist – Gene Therapy

Manylion swydd
Dyddiad hysbysebu: 19 Tachwedd 2025
Cyflog: £40,000 i £45,000 bob blwyddyn
Oriau: Llawn Amser
Dyddiad cau: 05 Rhagfyr 2025
Lleoliad: SK10 4TG
Gweithio o bell: Ar y safle yn unig
Cwmni: Bitrobius Genetics Ltd
Math o swydd: Parhaol
Cyfeirnod swydd: SMBGT25

Gwneud cais am y swydd hon

Crynodeb

Summary

We are seeking a Senior Molecular Cell Biologist to join our dynamic gene therapy team. We offer a competitive salary and benefits package including share options, health insurance and 25 days holiday plus bank holidays. A full-time position with a 35-hour week.

Company overview

Bitrobius Genetics is a pioneering biotechnology company that is developing Gentrafix™: a synthetic biology platform technology that has the potential to revolutionise the treatment of genetic diseases. Gentrafix will represent a technological breakthrough as the only platform capable of delivering therapeutic genes to most of the cells in an affected tissue or organ. We are located at Alderley Park, the UK’s largest science park, in the beautiful Cheshire countryside near to Manchester.

The role

An exciting full-time position in gene therapy, you will be an integral member of a small team working to develop Gentrafix for in vivo gene delivery, expression and editing of both nuclear and mitochondrial genes. You will initially construct and test plasmids to optimise plasmid replication and intercellular transmission in cell culture and develop assays to test the platform. The goal is to engineer experimental treatments for some of the most prevalent genetic diseases. The role will predominantly be laboratory-based and is a unique opportunity to gain valuable experience and influence the growth of the company. Key skills required include:

-Cell culture and cell engineering.
-Analysis of recombinant protein expression including western blot and ELISA.
-Designing and constructing plasmids in E. coli.
-Performing DNA extraction, PCR and qPCR.
-Gene editing including CRISPR.
-Thorough researching of relevant literature and writing reports to a high standard.

Experience of membrane biology or mitochondria would be advantageous but not essential.

The candidate

We are looking for a talented and enthusiastic scientist who would relish the opportunity to have a significant influence in our biotech start-up. We value applicants with industrial experience and the perspective that this brings. You must have a strong background in molecular and cell biology research in gene therapy, gene editing or recombinant protein expression in mammalian cells with:

-A PhD, or Masters degree and 5+ years industrial experience, in molecular or cell biology.
-A track record of undertaking original research.
-A capacity for independent thinking.
-Excellent problem-solving skills.
-Entitlement to work in the UK.

This is an exciting opportunity to work at the cutting edge of advanced genetic medicine. Please send a CV and cover letter by 5 December to: https://uk.indeed.com/job/senior-molecular-cell-biologist-65514633e43dc77a. We look forward to meeting you!

Gwneud cais am y swydd hon