Trial Manager / Clinical Research Practitioner II | Guy's and St Thomas' NHS Foundation Trust
| Posting date: | 10 June 2025 |
|---|---|
| Salary: | Not specified |
| Additional salary information: | £44,806 - £53,134 per annum inc HCA |
| Hours: | Part time |
| Closing date: | 11 July 2025 |
| Location: | London, SE1 0UN |
| Company: | Guys and St Thomas NHS Foundation Trust |
| Job type: | Contract |
| Job reference: | 7268508/196-RD315 |
Summary
We are seeking a dynamic and experienced Clinical Research Practitioner to manage theLISA study, a clinical trial investigating treatments for bacterial vaginosis and candida. This exciting study compares standard oral treatments to vaginal lactoferrin and includes both quantitative and qualitative components. The successful candidate will lead on all trial management activities including recruitment, data quality, participant follow-up, and sample handling, ensuring adherence to ICH-GCP standards.
This is a part-time position based across two main research sites:Burrell St Sexual Health ClinicandCurran General Practice in Clapham.
• Manage day-to-day operations of the LISA trial including recruitment, randomisation, consent, and follow-up of study participants.
• Conduct qualitative interviews with participants to support the study's mixed-methods design.
• Organise and lead Trial Management Group and Trial Steering Group meetings, presenting progress and recruitment updates.
• Liaise with Clinical Trials Unit to manage study database and randomisation system.
• Coordinate collaboration with internal departments (e.g., R&D, Pharmacy, Labs) and external bodies (e.g., IMP manufacturers).
• Develop and maintain trial-specific documentation, SOPs, and the Trial Master File (TMF).
• Organise and ensure quality control of participant sample packs and sample tracking, analysis, and storage.
• Support protocol amendment processes and represent the trial at conferences and stakeholder meetings.
You will be joining one of the UK’s most respected NHS Trusts, committed to delivering cutting-edge research that directly informs and enhances patient care. The Trust is a major centre for academic and clinical excellence and provides an inclusive, supportive environment for career development and research delivery.
Clinical and Communication Responsibilities
• Manage a caseload of participants, ensuring informed consent and compliance with trial protocols.
• Perform clinical assessments (e.g., vitals, sample collection, urinalysis) and support biological sample preparation.
• Report adverse events and deviations from protocol in a timely and professional manner.
• Maintain accurate and complete participant records and liaise effectively with the clinical team.
Research and Portfolio Management
• Assist in study setup, protocol reviews, and R&D submissions.
• Maintain accurate CRFs and ensure timely resolution of data queries.
• Monitor and report recruitment metrics, support study accrual efforts, and liaise with sponsors.
• Ensure all trial documentation is archived and compliant with regulatory requirements.
Management and Leadership
• Line manage junior research staff as required and contribute to performance appraisals.
• Lead on policy implementation and service quality improvements.
• Act as a role model and mentor within the research team and represent the Trust in external forums.
Education & Professional Development
• Maintain professional development through ongoing training and reflective practice.
• Contribute to SOP development and support educational activities across the research department.
Additional Responsibilities
• Ensure responsible use of research equipment and resources in line with study budgets.
• Work flexibly to meet the needs of the study, including occasional evenings or weekends.
• Foster cross-departmental collaboration and integration of research within clinical services.
This advert closes on Sunday 29 Jun 2025