Clinical Trials and Primary Care Pharmacist

Posting date:	20 May 2025
Salary:	Not specified
Additional salary information:	Negotiable
Hours:	Full time
Closing date:	20 June 2025
Location:	London, W67HY
Company:	NHS Jobs
Job type:	Permanent
Job reference:	A3071-25-0001

Summary

The following are the core responsibilities of the Role. There may be on occasion, a requirement to carry out other tasks; this will be dependent upon factors such as workload and staffing levels: To help to ensure HFP provides safe and efficient services within clinical trials in accordance with relevant regulations and guidance such as the Royal Pharmaceutical Society of Great Britains Professional Guidance on Pharmacy Services for Clinical Trials Review and put into place guidance from the specialist pharmacist service for provision of clinical trials To create excellent working knowledge of relevant regulation and guidance Liaise with local colleagues to arrange shadowing at local trusts and clinical trials providers with pharmacy team members Monitors pharmacy activities, on a regular basis, to ensure adherence to study protocols and dispensing procedures. To ensure that the documentation, processes and procedures for the handling of Investigational Medicines Products (IMPs) within the trials unit meet the current relevant UK and European legislation, ICH GCP guidelines and GMP principles required by the Medicines and Healthcare Regulatory Authority (MHRA), National Patient Safety Alerting System (NPSAS), Regional Pharmaceutical Quality Assurance Services and relevant clinical trial sponsors To participate in planning meetings in order to provide guidance at an early stage, on trial design and pharmacy processes for any clinical trial under consideration, ensuring pharmacy capacity has been considered To participate in sponsor led site selection and initiation visits To support seeking new commercial and academic trial opportunity To be responsible for co-ordinating the pharmaceutical input into the setting-up, design and running of clinical trials at the research unit. This will involve close liaison with pharmacy, nursing, medical staff and R&D To be responsible for the sign off of pharmacy clinical trial components, with support of Dr Wingfield To build a network of local pharmacy support and professionals of similar interest so we can incorporate further comments from appropriate specialist clinical and technical pharmacists if required Consults with other pharmacy personnel, to obtain information/expertise in support of the investigational drug trials, as required. To approve all pharmacy related clinical trial SOPs, policies, procedures and documents To approve all commercial, non-commercial and in-house clinical trials and associated paperwork e.g. prescriptions and labels, liaising as necessary with the lead of the clinical trials unit (Dr Wingfield) To provide advice and guidance to investigating teams on the planning and execution of in-house clinical trials To promote research and development in pharmacy practice to colleagues in the pharmacy team at PCN wide pharmacist meetings To take charge of the Pharmacy investigations into study issues and incidents involving IMP, ensuring appropriate documentation and completion of any actions To error report appropriately in-house and externally To lead MHRA, Sponsor and in-house GCP inspections for the pharmacy trials service if required with support of Dr Wingfield To establish and maintain a good working relationship with sponsors, monitors, auditors and regulatory authorities. To ensure that the confidentiality and security of information and data about study subjects and clinical trial studies are maintained and respected. To develop highly specialised knowledge so gain ability to provide complex advice on medicines including IMPs where information is lacking or when there are conflicting opinions and the client may be enquiring about potential contentious issues. To seek advice regarding pharmacy matters in clinical trials when required To manage the raising, completion and implementation of all relevant IMP and non-IMP documents, controlled procedures, risk assessments, feasibility assessments, prescriptions, dispensing protocols, accountability logs, and stock management records. To be responsible for the oversight and maintenance of dispensing procedures for all clinical trials To assess each trial for the need for a pharmacist clinical screen in conjunction with Dr Wingfield To ensure that safe dispensing practices are applied and adhered to at all times when dispensing and preparing Clinical Trial IMPs To accurately screen, dispense, check and counsel patients regarding their medication as required in accordance with the particular study protocol To ensure that health and safety and COSHH guidelines are managed within the clinical trials team To ensure all staff involved in clinical and final checking, dispensing and preparation and supply of IMPs have sufficient training and up to date knowledge in order to carry out their functions safely, effectively and in a timely manner. To act as a main contact with clinicians and sponsors in the event of an adverse event linked to a clinical trial To drive, plan and implement developments in the clinical trials service, in order to meet the needs of service users. To represent the pharmacy clinical trials department on appropriate governance and trial steering meetings To represent HFP at clinical trial or research networks at all levels. To use these networks to share best practice and to bring information and new ideas back to the Trust. Primary Care Pharmacist: a. Practice as an independent prescriber working within scope of practice b. Design and agree a repeat prescribing policy, taking responsibility for review of policy c. annually and implementation consistency across sites. d. Carry out face-to-face and telephone consultations with patients with minor illnesses, within the scope of practice. e. To provide medication review services with patients in the practice and during domiciliary visits to the local nursing home f. Visit vulnerable patients at home, prescribing changes to medications. g. To provide advice and support for patients with self-limiting conditions h. Encourage cost-effective prescribing within the practice i. Review all safety alerts ensuring the required actions are taken j. To reconcile medicines following patients discharge from hospital or clinic appointments k. Review medications for newly registered patients l. Implement and embed a robust repeat prescribing system m. To provide subject matter expertise on medication monitoring, implementing and embedding a system n. Carry out targeted medication reviews for high-risk patients. MUR Level 3 clinic, performing medication reviews, reviewing the need for medication and prescribing independently as required. o. To reauthorise medication for repeat prescribing within scope of practice p. Identify patients suitable for repeat prescribing, liaising with the relevant clinicians as required q. Review and implement safe prescribing systems for vulnerable patients, improving compliance r. Support clinicians with the management of patients suffering from drug and alcohol dependencies s. Actively signpost patients to the correct healthcare professional t. Assist with QOF targets u. Administer influenza and travel vaccines v. Perform routine clinical observations, prescribing changes to medication based on results. w. With appropriate training, run chronic disease clinics in all areas and integrate fully with chronic disease team established in practice. Prescribe treatment as necessary based on National and Local guidance. x. Manage multi-morbidity patients, prescribe where necessary and optimise medical therapy y. for best results. z. Contribute to the organisation and running of public health campaigns, including influenza. aa. Embed core skills with systm1 searches and utilise external data tools (e.g. WSIC / opioid dashboard) to support QIP. bb. To assess and address data from across the PCN for the purpose of QIP cc. To share learnings from QIP with external stakeholders and internally dd. Embed learning from QIP for legacy effect and onward improved care ee. Liaise with MDT team to support other professionals research and data projects e.g. GP Registrar, MPharm students, Undergraduates ff. Extend relationships to relevant educational and research partners Please see Job Description and Person Specification attachment for further details.