Director, Clinical Immunology
| Posting date: | 29 April 2026 |
|---|---|
| Hours: | Full time |
| Closing date: | 29 May 2026 |
| Location: | Oxford, Oxfordshire |
| Remote working: | Hybrid - work remotely up to 3 days per week |
| Company: | OMass Therapeutics Limited |
| Job type: | Permanent |
| Job reference: |
Summary
Job title: Director, Clinical Immunology
Job type: Full-time
Location: Oxford / hybrid working arrangements
Salary: Competitive salary
Deadline: 29th May 2026
Application submission: CV and cover letter via our website www.omass.com/working-here/
OMass Therapeutics is a biotechnology company based in Oxford discovering medicines against highly- validated target ecosystems, such as membrane proteins or intracellular complexes. The company’s unique OdyssION™ technology platform comprises novel biochemistry techniques, next-generation native mass spectrometry, and custom chemistry. OMass is advancing a pipeline of small-molecule therapeutics in rare diseases and immunological conditions that target solute carriers, complex-bound proteins, and GPCRs.
We are seeking a Clinical Immunologist to join our team. You will be part of a dynamic, innovative environment and become an integral part of our vision to address patients’ unmet needs while building Britain’s Biggest Biotech. You will provide internal and external-facing immunology clinical development expertise and leadership for the OMass immunology portfolio, reporting to the VP, Clinical Development, and collaborating with a focused and caring team.
Discover the impactful work OMass delivers and explore our Employee Value Proposition here https://www.omass.com/working-here.
Role Overview
• Partner with the Translational Pharmacology team to shape and deliver the company’s immunology strategy to develop a portfolio of differentiated and commercially viable immunology assets
• Lead clinical development strategy, planning and execution for OMass pipeline of first-in-class immunology assets
• Contribute to discovery and pre-clinical plans to deliver development candidates with highly differentiated target product profiles
• Drive efforts to establish clinical biomarker plans to demonstrate early proof-of-mechanism and value generation for early immunology assets
• Contribute to target identification and selection activities, including patient stratification strategies
Essential Experience, Skills and Qualities
• MD or MD/PhD with significant experience in immunology and drug development, and a strong track record of advancing novel immunology drug candidates through clinical trials, preferably in a biotech setting
• Industry recognition as a subject matter expert and extensive knowledge of immunology, particularly in autoimmune diseases
• Experience in designing and overseeing clinical trials, including familiarity with regulatory requirements
• Strong communication and interpersonal skills, with the ability to collaborate across multi-functional teams
• Strong presentation skills with the ability to present at Board level and to external stakeholders with credibility and confidence
• Strategic thinking capabilities and the ability to identify and solve complex problems
Role Responsibilities
• Lead all aspects of clinical development planning from phase 1 to registration with a multidisciplinary team for immunology assets, rapidly and efficiently maximising candidate molecule potential and differentiation with scientific rigour, and delivering critical data required to make decisions at each key milestone
• Lead a cross-functional clinical trial team to design and execute high-quality, innovative clinical studies within governance-approved timeline and budget commitments, collaborating effectively with internal colleagues and external partners
• Collaborate with discovery and preclinical teams to develop and deliver insightful translational plans
• Responsible for presentation of results and updates of projects at project, corporate and scientific meetings
• Establish and manage relationships with key opinion leaders and patient organisations to gain and incorporate insights to inform clinical strategy and operational decisions
• Engage in clinical development support across the portfolio
• Support Business Development, including due diligence activities
OMass Benefits
OMass offers an excellent benefits package, including:
• Private Health Insurance
• Health and well-being cashback scheme
• Life Assurance and Income Protection
• Participation in Employee Equity Scheme
• 25 days annual leave, plus bank holidays
• Pension Scheme offering 6% employer contribution
• Learning and Development Opportunities
• Company social events
Any queries relating to the role can be sent to hr@omass.com.
OMass Therapeutics values diversity and is committed to equality of opportunity. We also have a responsibility to ensure that all employees are eligible to work and live in the UK.
Job type: Full-time
Location: Oxford / hybrid working arrangements
Salary: Competitive salary
Deadline: 29th May 2026
Application submission: CV and cover letter via our website www.omass.com/working-here/
OMass Therapeutics is a biotechnology company based in Oxford discovering medicines against highly- validated target ecosystems, such as membrane proteins or intracellular complexes. The company’s unique OdyssION™ technology platform comprises novel biochemistry techniques, next-generation native mass spectrometry, and custom chemistry. OMass is advancing a pipeline of small-molecule therapeutics in rare diseases and immunological conditions that target solute carriers, complex-bound proteins, and GPCRs.
We are seeking a Clinical Immunologist to join our team. You will be part of a dynamic, innovative environment and become an integral part of our vision to address patients’ unmet needs while building Britain’s Biggest Biotech. You will provide internal and external-facing immunology clinical development expertise and leadership for the OMass immunology portfolio, reporting to the VP, Clinical Development, and collaborating with a focused and caring team.
Discover the impactful work OMass delivers and explore our Employee Value Proposition here https://www.omass.com/working-here.
Role Overview
• Partner with the Translational Pharmacology team to shape and deliver the company’s immunology strategy to develop a portfolio of differentiated and commercially viable immunology assets
• Lead clinical development strategy, planning and execution for OMass pipeline of first-in-class immunology assets
• Contribute to discovery and pre-clinical plans to deliver development candidates with highly differentiated target product profiles
• Drive efforts to establish clinical biomarker plans to demonstrate early proof-of-mechanism and value generation for early immunology assets
• Contribute to target identification and selection activities, including patient stratification strategies
Essential Experience, Skills and Qualities
• MD or MD/PhD with significant experience in immunology and drug development, and a strong track record of advancing novel immunology drug candidates through clinical trials, preferably in a biotech setting
• Industry recognition as a subject matter expert and extensive knowledge of immunology, particularly in autoimmune diseases
• Experience in designing and overseeing clinical trials, including familiarity with regulatory requirements
• Strong communication and interpersonal skills, with the ability to collaborate across multi-functional teams
• Strong presentation skills with the ability to present at Board level and to external stakeholders with credibility and confidence
• Strategic thinking capabilities and the ability to identify and solve complex problems
Role Responsibilities
• Lead all aspects of clinical development planning from phase 1 to registration with a multidisciplinary team for immunology assets, rapidly and efficiently maximising candidate molecule potential and differentiation with scientific rigour, and delivering critical data required to make decisions at each key milestone
• Lead a cross-functional clinical trial team to design and execute high-quality, innovative clinical studies within governance-approved timeline and budget commitments, collaborating effectively with internal colleagues and external partners
• Collaborate with discovery and preclinical teams to develop and deliver insightful translational plans
• Responsible for presentation of results and updates of projects at project, corporate and scientific meetings
• Establish and manage relationships with key opinion leaders and patient organisations to gain and incorporate insights to inform clinical strategy and operational decisions
• Engage in clinical development support across the portfolio
• Support Business Development, including due diligence activities
OMass Benefits
OMass offers an excellent benefits package, including:
• Private Health Insurance
• Health and well-being cashback scheme
• Life Assurance and Income Protection
• Participation in Employee Equity Scheme
• 25 days annual leave, plus bank holidays
• Pension Scheme offering 6% employer contribution
• Learning and Development Opportunities
• Company social events
Any queries relating to the role can be sent to hr@omass.com.
OMass Therapeutics values diversity and is committed to equality of opportunity. We also have a responsibility to ensure that all employees are eligible to work and live in the UK.