Cognitive Disorders Clinical Research Fellow
| Posting date: | 02 March 2026 |
|---|---|
| Salary: | Not specified |
| Additional salary information: | £65,048 per annum + London weighting, pro-rata. |
| Hours: | Part time |
| Closing date: | 01 April 2026 |
| Location: | London, WC1N 3BG |
| Company: | University College London Hospital |
| Job type: | Contract |
| Job reference: | 7841818/309-UCLH-7544 |
Summary
A Vacancy at University College London Hospitals NHS Foundation Trust.
University College London Hospitals NHS Foundation Trust invites candidates to apply for an exciting opportunity as a full-time Clinical Research Fellow post based at the Dementia Research Centre, at the National Hospital for Neurology and Neurosurgery.
We are looking for an enthusiastic, committed individual with excellent communication and clinical skills to join our clinical research team at the Dementia Research Centre. This centre is internationally renowned for performing groundbreaking research into dementia, with particular focus on familial dementias and translational research. Early phase clinical trials are a high priority: in particular, looking for disease modification therapies using cutting edge methods such as immunotherapy and gene silencing. Alongside the interventional trials, we run longitudinal cohort studies in normal ageing (1946) genetic FTD (GENFI) and AD (DIAN) looking for biomarkers of early disease and to better understand the pathophysiology. We work closely with basic science colleagues at the Dementia Research Institute and collaborate on multiple translational projects.
This post would suit someone who is looking to enhance their understanding of research in dementia without initial commitment to a PhD.
• Applicants must have a relevant medical degree andbe fully registered with the GMC by the expected start date (ASAP). A good knowledge of neurology and an interest in research are essential.
The successful candidate will be primarily involved in clinical trials as part of the DRC clinical trials unit led by Cath Mummery. This is a multidisciplinary team with extensive experience in first in human, highly complex trials. The candidate will be able to take part in the cognitive disorders clinics and other educational opportunities at the DRC. They will also have the opportunity to get involved in other aspects of research.
University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.
We provide first-class acute and specialist services across eight sites:
• University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
• National Hospital for Neurology and Neurosurgery
• Royal National ENT and Eastman Dental Hospitals
• University College Hospital Grafton Way Building
• Royal London Hospital for Integrated Medicine
• University College Hospital Macmillan Cancer Centre
• The Hospital for Tropical Diseases
• University College Hospital at Westmoreland Street
We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women’s health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.
We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.
For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.
Please note, due to anticipated high volumes of applications, this vacancy may close earlier than the listed closing date. You are advised not to delay submitting your completed application
MAIN DUTIES:
• To work closely and co-operatively with other members of the group to deliver the highest standards of clinical care to patients and study participants
• To work closely with other members of the DRC and external collaborators and sponsors to ensure that the highest quality clinical data are collected.
• To work with the clinical trials team and LWENC staff to ensure delivery to target in drug trials, to work with the clinical trials lead, other PIs and Clinical Research Fellows to recruit and screen potential research subjects and ensure the on-going maintenance of clinical and research records.
• To be trained in intra-thecal administration of gene silencing therapies and administer as part of trial protocol.
• To treat infusion related reactions and other medical emergencies; ideally to have an advanced life support certificate.
• To assist with a cognitive clinic a week under consultant neurologist supervision.
• To attend patient support groups and be involved in community engagement as required.
• To undertake analysis of imaging and other data sets and contribute to scientific writing.
• To assist in the preparation of materials (e.g., slides, diagrams) for presentation and/or publication by members of the DRC.
• To assist in the development of the dementia research programme, promoting on-going studies, monitoring recruitment rates and encouraging referrals.
• To support the recruitment team screening the right patient for the right study and to manage disappointing outcomes for patients, such as screen fails or early trial terminations.
• Provision of teaching on topics related to the post holder’s work as requested by the line manager.
• Contributing to the department’s multidisciplinary research projects within the strategy.
• Preparing and analysing data for publications for dissemination of research and for presentation at international conferences as well as internal meetings at UCL, and meetings with external collaborators.
• Ensuring the highest standard of record keeping, maintaining accurate, complete, and up to date records.
• Ensuring confidentiality is maintained as applicable.
• Attending and contributing to Departmental, Institutional, and other meetings as appropriate.
• Acting at all times in accordance with the highest professional standards and ensuring that these are maintained in the delivery of all aspects of research.
• All staff are required to act professionally, co-operatively, and flexibly in line with the requirements of the post.
This post is based within the Cognitive disorders department at the National Hospital for Neurology and Neurosurgery (NHNN)which is the largest division within the Specialist Hospitals Board. The NHNN is an internationally renowned hospital for clinical practice and world-class clinical research in neurosciences. It is also closely associated with the Institute of Neurology (ION). Together, the NHNN and ION are regarded as the premier neurosciences centre in the UK. In addition to Neurology and Neurosurgery, the NHNN provides comprehensive services in Neurorehabilitation, Neuro-critical care, and Neuropsychiatry. The NHNN receives secondary, tertiary, and quaternary referrals from across the UK and internationally.
The UCL Dementia Research Centre (DRC)is a key part of UCL ION and a hub for clinical research into various forms of dementia. Our work focuses on identifying and understanding the disease processes that cause dementia, the factors that influence these disease processes, and how best to support people with dementia and their families. In addition to our research, we also provide a cognitive disorders clinic within the National Hospital for Neurology and Neurosurgery; research is embedded into the clinic so that all patients have the opportunity to participate.
Come and be a part of the best NHS trust in England to work for, according to our staff*
* UCLH top trust to work at in England - In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England – for the third year in a row.
UCLH recognises the benefits of flexible working for staff – To find out more, visit: Flexible working.
To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?
This advert closes on Monday 16 Mar 2026
University College London Hospitals NHS Foundation Trust invites candidates to apply for an exciting opportunity as a full-time Clinical Research Fellow post based at the Dementia Research Centre, at the National Hospital for Neurology and Neurosurgery.
We are looking for an enthusiastic, committed individual with excellent communication and clinical skills to join our clinical research team at the Dementia Research Centre. This centre is internationally renowned for performing groundbreaking research into dementia, with particular focus on familial dementias and translational research. Early phase clinical trials are a high priority: in particular, looking for disease modification therapies using cutting edge methods such as immunotherapy and gene silencing. Alongside the interventional trials, we run longitudinal cohort studies in normal ageing (1946) genetic FTD (GENFI) and AD (DIAN) looking for biomarkers of early disease and to better understand the pathophysiology. We work closely with basic science colleagues at the Dementia Research Institute and collaborate on multiple translational projects.
This post would suit someone who is looking to enhance their understanding of research in dementia without initial commitment to a PhD.
• Applicants must have a relevant medical degree andbe fully registered with the GMC by the expected start date (ASAP). A good knowledge of neurology and an interest in research are essential.
The successful candidate will be primarily involved in clinical trials as part of the DRC clinical trials unit led by Cath Mummery. This is a multidisciplinary team with extensive experience in first in human, highly complex trials. The candidate will be able to take part in the cognitive disorders clinics and other educational opportunities at the DRC. They will also have the opportunity to get involved in other aspects of research.
University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.
We provide first-class acute and specialist services across eight sites:
• University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
• National Hospital for Neurology and Neurosurgery
• Royal National ENT and Eastman Dental Hospitals
• University College Hospital Grafton Way Building
• Royal London Hospital for Integrated Medicine
• University College Hospital Macmillan Cancer Centre
• The Hospital for Tropical Diseases
• University College Hospital at Westmoreland Street
We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women’s health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.
We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.
For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.
Please note, due to anticipated high volumes of applications, this vacancy may close earlier than the listed closing date. You are advised not to delay submitting your completed application
MAIN DUTIES:
• To work closely and co-operatively with other members of the group to deliver the highest standards of clinical care to patients and study participants
• To work closely with other members of the DRC and external collaborators and sponsors to ensure that the highest quality clinical data are collected.
• To work with the clinical trials team and LWENC staff to ensure delivery to target in drug trials, to work with the clinical trials lead, other PIs and Clinical Research Fellows to recruit and screen potential research subjects and ensure the on-going maintenance of clinical and research records.
• To be trained in intra-thecal administration of gene silencing therapies and administer as part of trial protocol.
• To treat infusion related reactions and other medical emergencies; ideally to have an advanced life support certificate.
• To assist with a cognitive clinic a week under consultant neurologist supervision.
• To attend patient support groups and be involved in community engagement as required.
• To undertake analysis of imaging and other data sets and contribute to scientific writing.
• To assist in the preparation of materials (e.g., slides, diagrams) for presentation and/or publication by members of the DRC.
• To assist in the development of the dementia research programme, promoting on-going studies, monitoring recruitment rates and encouraging referrals.
• To support the recruitment team screening the right patient for the right study and to manage disappointing outcomes for patients, such as screen fails or early trial terminations.
• Provision of teaching on topics related to the post holder’s work as requested by the line manager.
• Contributing to the department’s multidisciplinary research projects within the strategy.
• Preparing and analysing data for publications for dissemination of research and for presentation at international conferences as well as internal meetings at UCL, and meetings with external collaborators.
• Ensuring the highest standard of record keeping, maintaining accurate, complete, and up to date records.
• Ensuring confidentiality is maintained as applicable.
• Attending and contributing to Departmental, Institutional, and other meetings as appropriate.
• Acting at all times in accordance with the highest professional standards and ensuring that these are maintained in the delivery of all aspects of research.
• All staff are required to act professionally, co-operatively, and flexibly in line with the requirements of the post.
This post is based within the Cognitive disorders department at the National Hospital for Neurology and Neurosurgery (NHNN)which is the largest division within the Specialist Hospitals Board. The NHNN is an internationally renowned hospital for clinical practice and world-class clinical research in neurosciences. It is also closely associated with the Institute of Neurology (ION). Together, the NHNN and ION are regarded as the premier neurosciences centre in the UK. In addition to Neurology and Neurosurgery, the NHNN provides comprehensive services in Neurorehabilitation, Neuro-critical care, and Neuropsychiatry. The NHNN receives secondary, tertiary, and quaternary referrals from across the UK and internationally.
The UCL Dementia Research Centre (DRC)is a key part of UCL ION and a hub for clinical research into various forms of dementia. Our work focuses on identifying and understanding the disease processes that cause dementia, the factors that influence these disease processes, and how best to support people with dementia and their families. In addition to our research, we also provide a cognitive disorders clinic within the National Hospital for Neurology and Neurosurgery; research is embedded into the clinic so that all patients have the opportunity to participate.
Come and be a part of the best NHS trust in England to work for, according to our staff*
* UCLH top trust to work at in England - In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England – for the third year in a row.
UCLH recognises the benefits of flexible working for staff – To find out more, visit: Flexible working.
To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?
This advert closes on Monday 16 Mar 2026
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