Clinical Operations Manager | University College London Hospitals NHS Foundation Trust

Posting date:	18 September 2025
Salary:	Not specified
Additional salary information:	£64,156 - £71,148 per annum inclusive of HCAS
Hours:	Full time
Closing date:	18 October 2025
Location:	London, WC1N 3BG
Company:	University College London Hospital
Job type:	Contract
Job reference:	7486059/309-UCLH-6841

Summary

We are seeking an experienced and solutions-focused Clinical Operations Manager to lead the epilepsy clinical trials portfolio at the National Hospital for Neurology and Neurosurgery (NHNN). This is an excellent opportunity for a motivated leader with strong operational, financial, and governance expertise to shape the future of epilepsy research across two internationally recognised sites.

Based across NHNN Queen Square (London) and the Chalfont Centre for Epilepsy (Buckinghamshire), you will oversee study setup, trial delivery, and financial sustainability of both commercial and non-commercial trials, working closely with Principal Investigators, Senior Research Nurses, and the UCL/UCLH Joint Research Office. This is a strategic yet hands-on role where you will strengthen trial capacity, accelerate setup timelines, and ensure high-quality, compliant delivery. You will also line manage members of the research delivery team, supporting staff recruitment, development, and workload allocation. Acting as a key contact for investigators, sponsors, CROs, and regulators, you will represent UCLH as a leading site for epilepsy research.

The ideal candidate will combine leadership with problem-solving skills, thrive in collaboration, and be motivated to drive innovation in clinical research. You will ensure studies are delivered safely, efficiently, and in line with GCP and regulatory requirements across both locations.

As Clinical Operations Manager, you will lead the delivery of a diverse portfolio of epilepsy clinical trials across NHNN Queen Square (London) and the Chalfont Centre for Epilepsy (Buckinghamshire). You will take responsibility for driving trial set-up, monitoring progress, and ensuring studies are delivered safely, on time, and to the highest regulatory standards.

You will line manage research nurses and guide the wider research delivery team, supporting recruitment, training, and development to build a motivated and skilled workforce. A key part of your role will be strengthening collaboration with investigators, industry partners, and regulators, while ensuring the financial sustainability of the portfolio through accurate and timely income recovery.

This is a role for someone who thrives on leadership and problem-solving. Whether streamlining trial processes, guiding staff, or representing UCLH at national and industry forums, you will be central to advancing research that improves the lives of people with epilepsy.

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.


We provide first-class acute and specialist services across eight sites:

• University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)

• National Hospital for Neurology and Neurosurgery

• Royal National ENT and Eastman Dental Hospitals

• University College Hospital Grafton Way Building

• Royal London Hospital for Integrated Medicine

• University College Hospital Macmillan Cancer Centre

• The Hospital for Tropical Diseases

• University College Hospital at Westmoreland Street



We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women’s health and the treatment of cancer, infection, neurological,gastrointestinaland oral disease. It has world class support services including critical care, imaging, nuclearmedicineandpathology.


Weare committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.


For the full Person Specification and more informationregardingthe main responsibilities of this role, please refer to the attached Job Description.

The post holder will be employed by theClinical Department of Epilepsyat University College Hospitals Foundation Trust.

We are offering:
• A job in a motivated and highly effective friendly team
• A supportive training and development environment

The post is a fixed term 12-month contract funded by the BRC. There is potential for this FTC to be extended in the future.

LOCATION: The role is split across both sites (NHNN and Chalfont)with days of attendance at each site to be agreed with supervisor based on service needs. Some remote and flexible working will be supported in line with team requirements.

INTERVIEW: A 5-10minute presentation will be required for the interview. The topic will be shared with applicants at time of shortlisting.


Come and be a part of the best NHS trust in England to work for, according to our staff*


*UCLH top trust to work at in England- In the most recentNHS staff surveyUCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England – for the third year in a row.


UCLH recognises the benefits of flexible working for staff – To find out more, visit:Flexible working. 


To discover more about what makes UCLHa great placeto work, visit:Why Choose UCLH?



This advert closes on Thursday 2 Oct 2025

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