Senior Genomics Technician | Guy's and St Thomas' NHS Foundation Trust
| Posting date: | 29 April 2026 |
|---|---|
| Salary: | Not specified |
| Additional salary information: | £47,951 - £56,863 p.a. inc HCA |
| Hours: | Full time |
| Closing date: | 29 May 2026 |
| Location: | London, SE1 9RT |
| Company: | Guys and St Thomas NHS Foundation Trust |
| Job type: | Permanent |
| Job reference: | 7925702/196-RD474M |
Summary
We are seeking to appoint a highly motivatedSenior Genomics Technicianto join the Genomics Research Platform and Single Cell Laboratory within the R&D Department at Guy’s and St Thomas’ NHS Foundation Trust.
Our laboratory employs state-of-the-art genomics technologies to accelerate the translation of research into clinical applications. This is an exciting opportunity for an individual with a strong interest in genomics to contribute to cutting-edge research projects.
The successful candidate will play a key role in supporting our genomics service provision, enabling both academic and clinical research projects. Experience is next-generation sequencing (NGS) is essential, and experience with single-cell or spatial transcriptomics technologies is highly desirable. In this role, you will contribute to advancing innovative research with the ultimate aim of improving patient outcomes.
As a Senior Genomics Technician, you will undertake scientific projects using a wide range of genomics workflows, driving experiments inbulk-cell sequencing,single-cell analysis, andspatial transcriptomics, providing critical insights for our research objectives. You will play a pivotal role in theoptimisation and validation of R&D workflows, evaluating and integrating emerging, cutting-edge technologies into our core pipeline. Working within a collaborative team, you will provide essential technical support and mentorship, ensuring that high-quality data and project outputs are delivered with precision and efficiency.
You will hold at least a BSc (or equivalent) in Biology/Life Sciences or relevant discipline plus experience gained through working in a research/service lab. Knowledge, skills and experience in genomics techniques is essential.
Key responsibilities:
• Workflow execution: Perform end-to-end genomics experiments, from sample preparation to library construction to sequencing, using state-of-the-art platforms.
• Innovation and R&D: Contribute to the development and refinement of lab protocols to enhance sensitivity, throughput and data quality.
• Technical expertise: As the technical expert in genomics workflows, provide training and guidance to junior team members, service users and collaborators.
• Operational Excellence: Maintain rigorous quality control standards and manage project timelines to ensure seamless delivery of results.
TheGenomics Research Platformat Guy’s & St Thomas’ NHS Foundation Trust (GSTFT) and King’s College London (KCL) is a premier collaboration between one of the UK’s largest and most successful NHS Trusts and a world-leading research university.
Operating as both a specialist service provider and a dedicated R&D facility, the Platform bridges the gap between innovative science and clinical application. Our multidisciplinary team of highly trained scientists possesses deep expertise in single-cell genomics and Next-Generation Sequencing (NGS), supported by a streamlined bioinformatics service to facilitate a broad range of high-impact translational research studies.
We are seeking a candidate for this exciting and challenging role who possesses a robust technical background, a commitment to laboratory excellence, and strong communication skills to support our evolving research portfolio.
TheGenomics Research Platform, a prestigious collaboration betweenGuy’s & St Thomas’ NHS Foundation Trust (GSTT)andKing’s College London (KCL), is seeking a highly motivatedSenior Genomics Technician. This permanent position offers an exciting opportunity to work at the forefront of a rapidly evolving field, contributing to both day-to-day service provision and innovative R&D projects.
As a key member of our specialist team, you will utilise a range of advanced molecular biology techniques to process samples using the latest genomics platforms. This role is ideal for a detail-oriented individual looking to advance their career within a high-impact, multidisciplinary environment that bridges clinical excellence and world-class research.
Main Duties and Responsibilities
• Service Provision:Deliver high-quality genomics services to platform users, including single-cell transcriptomics profiling, spatial transcriptomics, and bulk DNA/RNA sequencing.
• Operational Excellence:Maintain meticulous records of all laboratory work and service operations for assigned projects, ensuring full traceability and data integrity.
• Collaboration & Communication:Work synergistically with team members and key stakeholders across GSTT and KCL to ensure a streamlined and efficient service.
• Research & Development:Actively contribute to the development and refinement of new Standard Operating Procedures (SOPs) and experimental protocols.
• Scientific Engagement:Participate in group meetings, contribute to data discussions, and present experimental findings to the wider team.
Qualifications and Experience
• BSc/MSc/PhD in Biomedical Science or an equivalent discipline with a proven track record in molecular biology workflows.
• Minimum of 3 years of experience in genomics/molecular biology, specifically within a research or service laboratory environment.
• Hands-on experience in manual or automated library preparation for Next-Generation Sequencing (NGS).
• Ability to strictly follow SOPs and worksheets with exceptional attention to detail to ensure reproducible results.
• Proven ability to work independently and complete complex projects within defined timelines and budgetary constraints.
• A fast learner who is receptive to specialised training and comfortable working under close supervision during the initial training period.
This advert closes on Wednesday 13 May 2026