Clinical Research Fellow - Late Phase | The Christie NHS Foundation Trust

Posting date:	17 March 2026
Salary:	Not specified
Additional salary information:	£52,656 - £73,992 Per Annum Pro Rata
Hours:	Full time
Closing date:	16 April 2026
Location:	Manchester, M20 4BX
Company:	The Christie NHS Foundation Trust
Job type:	Contract
Job reference:	7879873/413-MD-C2025-24949-OO

Summary

An exciting opportunity has arisen within the Research and Innovation Division at The Christie. We are looking to appoint a Senior Clinical Fellow to provide medical support to the for the Late phase Pan Tumour Research Team.

With consultant oversight, you will be responsible for seeing new referrals, follow-ups & managing the patient throughout all aspects of their trial experience.

The position is suitable for those on a specialist oncology training pathway (preference will be given to those who are towards the end or having completed this), and who wish to gain further experience in experimental medicine and late-phase multi-cohort trials with a focus on tumour agnostic treatments, clinical pharmacology trials & translational research. Our teams deliver trials in all major solid tumour types.

The position requires an ability to understand and deliver late-phase multi-cohort trials, liaising across a range of clinical, academic and administrative staff throughout the Trust and with external organisations (pharmaceutical and biotech industry partners, academic institutions and other hospitals).

The portfolio includes a diverse range of clinical research trials. Following training, you will be expected to participate in these studies as a sub-investigator. These may include late phase multi cohort basket trials of small molecule inhibitors, next-generation chemotherapy trials, combination / multi-modality late phase trials, advanced therapy trials, molecular characterisation / translational studies, radiotherapy trials.

You will be involved in managing all aspects of trial patients (both in outpatient & in-patients setting), across a diverse range of solid tumours, through new patient consultation, consent & screening patients & reviewing patients at follow-up appointments.

You will be expected to attend safety review committee meetings to discuss trial patients. This will involve close liaison with the Principal Investigators. In addition, you will interface with external stakeholders such as CROs & pharmaceutical sponsors.

You will be expected to undertake the administrative duties associated with the care of our patients. You will be given opportunities and will be encouraged to be involved in the development & planning of new studies.

There is potential to present your research work, and you will be expected to be involved in writing papers and reviews. You will also be required to undergo an annual appraisal.

The Christie is one of Europe’s leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country.

We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years.

We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.

The medical establishment provides 1-5 Consultant Medical Oncologists

The appointee will be based at The Christie and will provide senior input to the PAN Tumour Research Team.

•RESEARCH: A diverse range of PAN Tumour research are in progress within the team and, following training, the post holder will be expected to participate in these studies as a co-/sub-investigator. You will be involved in managing all aspects of trial patients, across a diverse range of solid tumours, through new patient consultation, consent and screening patients and reviewing patients at follow-up appointments. Primarily, patients are seen in the outpatient setting but with some inpatient cover. The appointee is required to attend 3 trial outpatient clinics per week (see indicative timetable).

You will be expected to attend Safety Review Committee meetings (usually remotely) to discuss trial patients. This will involve close liaison with the PAN Principal Investigators, disease-site specific consultants across the Trust and other members of the team. In addition, you will interface with external stakeholders such as other NHS, academic and industry partners.
You will be expected to attend weekly PAN operational meetings to discuss portfolio oversight.

Continuing Professional Development
The Trust supports the requirements for continuing professional development (CPD) as laid down by the GMC and surgical colleges and is committed to providing time and financial support for these activities.

Role Planning
ROLE: The successful candidate will be recruited as a Senior Clinical Fellow in the PAN tumour clinical Research team.

• RESEARCH: A diverse range of clinical research trials are in progress and, following training, the post holder will be expected to participate in these studies as a sub-investigator. These include Late phase trials of small molecule inhibitors, next-generation chemotherapy trials, combination / multi-modality phase I trials, molecular characterisation / translational studies.

The post holder will be involved in managing all aspects of trial patients, through new patient consultation, consent and screening patients and reviewing patients at follow-up appointments. Primarily, patients are seen in the outpatient setting but with some inpatient cover. The appointee is required to attend 4-5 trial outpatient clinics per week (see indicative timetable).

The post holder will be expected to attend Safety Review Committee meetings (usually remotely) to discuss trial patients. This will involve close liaison with the trial Principal Investigators, referring consultant body across the Trust and other members of the team. In addition, the post-holder will interface with external stakeholders such as CROs and pharmaceutical sponsors.

The post-holder will be expected to attend monthly molecular tumour board meetings to discuss trial patients and to agree opportunities for patients to enroll into PAN Tumour trials.

• PROTOCOLS: The post holder will be expected to undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to harness opportunities to be involved in the development and planning of new studies.

• PROFESSIONAL DEVELOPMENT: The Clinical Fellow will maintain a level of continuing professional development consistent with the recommendations of the Royal College of Physicians. Appropriate arrangements for study leave will be made in conjunction with colleagues. There is the potential to present research work and the post holder will be expected to be involved in audit, writing papers and reviews. The post holder will also be required to undergo an annual appraisal.

• TEACHING COMMITMENT:

a) Undergraduate
The appointee will be required to contribute to the undergraduate teaching of medical students on oncology topics.
b) Postgraduate
There is a busy postgraduate teaching programme and staff are often requested to lecture on relevant topics. The post holder will be expected to contribute actively to the education of junior doctors, specialty trainees and fellows on the team.
The post holder will also be expected to help in the training of nursing and multi-disciplinary staff in both in-patient and outpatient departments.

• CLINICAL GOVERNANCE: The post holder will be expected to participate in all relevant aspects of clinical governance, including maintaining up to date protocols, guidelines and clinical audit, under the supervision of the other consultants in the team.

• AUDIT: The appointee will play a full role in clinical audit as a member of The Christie Medical Staff Committee. The appointee will develop, supervise and deliver team audit projects.

On call Commitments
This role does not require participation in the on-call rota. (However out of hours/weekend shifts may be occasionally required to provide medical care to trial patients in our Clinical Research Facility.


This advert closes on Tuesday 31 Mar 2026

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