Clinical Research Fellow in Human Infection Challenge
| Posting date: | 11 February 2026 |
|---|---|
| Salary: | £52,655.00 to £73,992.00 per year |
| Additional salary information: | £52655.00 - £73992.00 a year |
| Hours: | Full time |
| Closing date: | 23 February 2026 |
| Location: | London, W12 0NN |
| Company: | NHS Jobs |
| Job type: | Contract |
| Job reference: | N0047-26-0011 |
Summary
The programme will start recruiting volunteers in mid-2026, and we anticipate the successful applicant will take up this position in March 2026. You will hold an honorary contract with the appropriate NHS Trusts and be expected to take on clinical responsibilities appropriate to your level of experience expertise, with training in study-specific areas provided: Clinical study delivery Assist with the setup and day-to-day management and delivery of the Staphylococcus aureus human challenge and other experimental vaccination or infection studies Assist with recruitment and screening of healthy volunteers. Provide direct clinical care to study participants admitted for S. aureus skin challenge, in liaison with the research nurses and study PIs. Provide direct clinical care to study participants admitted for respiratory viral controlled human infection models, in liaison with the research nurses and study PIs Support delivery of other clinical studies (including trials) within Dr Aggarwals group. Acting as a point of contact for study participants to provide clinical advice and care before, during and after infectious agent challenge, under the supervision of the study PI. Co-ordinate the development of study protocols and associated study documentation. Prepare safety reports and briefings for the data safety monitoring committee. Ensure adherence to the study protocols and compliance with regulatory requirements. Work with the rest of the clinical team, in particular the lead research nurse and clinical project manager, to ensure all clinical research conducted is compliant with Good Clinical Practice. Academic development, training and supervision Possibility of enrolling for an MD(Res) or equivalent if desired and as appropriate Participate in the analysis of immune responses using cellular and molecular immunology techniques if desired and as appropriate. Participate in the analysis of S. aureus load dynamics and evolution using genomics if desired and as appropriate. Participate in the analysis of host microbiome determinants of, and dynamics during, S aureus infection if desired and as appropriate. Training of study associated personnel. Troubleshooting issues while maintaining and developing good relationships with researchers and clinicians associated with the study in a variety of different settings. Identifying and developing further research themes which may be developed within this or newly conceived studies.