Warning
This job advert has expired and applications have closed.
12852 - Post Doctoral Research Fellow
| Posting date: | 01 August 2025 |
|---|---|
| Salary: | £41,064 to £48,822 per year |
| Hours: | Full time |
| Closing date: | 14 August 2025 |
| Location: | Edinburgh |
| Remote working: | Hybrid - work remotely up to 3 days per week |
| Company: | University of Edinburgh |
| Job type: | Contract |
| Job reference: | 12852 |
Summary
Grade UE07: £41,064 - £48,822 per annum
CMVM / Deanery of Clinical Sciences / Centre for Cardiovascular Sciences
Full time: 35 hours per week
Fixed-Term: until 28/02/2027 (possibility of extension until 30/06/27)
The Opportunity:
We are seeking applications for a PDRA to join the dynamic research group of Dr Denby working on an exciting translational MRC funded study in which we are targeting scar-associated monocyte-derived macrophages (SAMac) to reduce fibrosis and the mechanisms associated with this. This project is in collaboration with the Ramachandran and Walmsley research labs of the Institute of Regeneration and Repair (IRR). This cutting-edge project involves sc/sn RNA sequencing and analysis of human and mouse kidney and liver samples, spatial transcriptomics, multiplex tissue staining, informative transgenic animal studies and metabolomics. The Denby lab is located in the Institute of Neuroscience and Cardiovascular Research (INCR) and is part of Edinburgh Kidney (https://edinburghkidney.co.uk/). The studies to be undertaken will be conducted between INCR and the IRR.
This post is full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.
Your skills and attributes for success:
The candidate must have a PhD (submitted or obtained) in immunology / biological sciences or related.
Strong theoretical knowledge of the mechanisms driving fibrosis.
Theoretical knowledge / experience of the application of flow cytometry and cell sorting.
Experience in metabolomics and/or immunometabolism
Experience in bioinformatic analysis of sc/sn RNA sequencing data
Practical knowledge of cell culture and immunostaining.
Knowledge of pre-clinical models of fibrosis.
CMVM / Deanery of Clinical Sciences / Centre for Cardiovascular Sciences
Full time: 35 hours per week
Fixed-Term: until 28/02/2027 (possibility of extension until 30/06/27)
The Opportunity:
We are seeking applications for a PDRA to join the dynamic research group of Dr Denby working on an exciting translational MRC funded study in which we are targeting scar-associated monocyte-derived macrophages (SAMac) to reduce fibrosis and the mechanisms associated with this. This project is in collaboration with the Ramachandran and Walmsley research labs of the Institute of Regeneration and Repair (IRR). This cutting-edge project involves sc/sn RNA sequencing and analysis of human and mouse kidney and liver samples, spatial transcriptomics, multiplex tissue staining, informative transgenic animal studies and metabolomics. The Denby lab is located in the Institute of Neuroscience and Cardiovascular Research (INCR) and is part of Edinburgh Kidney (https://edinburghkidney.co.uk/). The studies to be undertaken will be conducted between INCR and the IRR.
This post is full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.
Your skills and attributes for success:
The candidate must have a PhD (submitted or obtained) in immunology / biological sciences or related.
Strong theoretical knowledge of the mechanisms driving fibrosis.
Theoretical knowledge / experience of the application of flow cytometry and cell sorting.
Experience in metabolomics and/or immunometabolism
Experience in bioinformatic analysis of sc/sn RNA sequencing data
Practical knowledge of cell culture and immunostaining.
Knowledge of pre-clinical models of fibrosis.