Senior Radiopharmacy Technician | The Christie NHS Foundation Trust

Posting date:	19 June 2025
Salary:	Not specified
Additional salary information:	£29,970 - £36,483 per annum pro rata
Hours:	Full time
Closing date:	19 July 2025
Location:	Manchester, M20 4BX
Company:	The Christie NHS Foundation Trust
Job type:	Permanent
Job reference:	7291251/413-95449-CMPE-SD

Summary

We are looking for an enthusiastic and motivated Radiopharmaceutical Technologist with experience in aseptic dispensing to join our dynamic and expanding Radiopharmacy team. Experience of Radiopharmacy is desirable but full support and training will be provided to candidates who meet the other specifications.

Consideration would be given to a less experienced applicant to join the team as a trainee.

Applicants must have the ability to work in an aseptic unit under current GMP guidelines and local rules. The successful candidates will be responsible, under the supervision of the Production Manager, for the delivery of Radiopharmacy Aseptic Services, including participation in and supervising of aseptic dispensing and manufacturing activities. They would also participate in the quality control of the radiopharmaceuticals and contribute to the day to day running of the department in a proactive manner.

The Christie is one of Europe’s leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country.

We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years.

We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.

The Radiopharmacy was commissioned in 2009 and operates under two MHRA licences: Specials and Wholesale Dealers.

The Christie Radiopharmacy supplies radiopharmaceuticals to nine Nuclear Medicine departments and produces more than 7,000 vials per year, making it the largest Radiopharmacy in the North West region. The Christie Radiopharmacy is also pioneering the use of Ga-68 radiopharmaceuticals and plays a key role supporting the NET service (ENETS Centre of Excellence).

DUTIES AND RESPONSIBILITIES

1. Regional Radiopharmacy

To be part of the team that carries out the daily production of radiopharmaceuticals within the Regional Radiopharmacy, in compliance with the requirements of The Human Medicine Regulations 2012, The Ionising Radiation (Medical Exposure) Regulations 2017 and amendment 2024, The Ionising Radiations Regulations 2017 and The Environmental Permitting Regulations. This includes:

1.1 Receipt of orders from customer departments

1.2 Preparation of the Radiopharmacy prior to each production run

1.3 Preparation of materials prior to Radiopharmacy production runs, including radionuclide generators

1.4 Participation in the complex processes for production of Tc-99m labelled radiopharmaceuticals using aseptic techniques, and working with due speed and efficiency.

1.5 Participation in the complex processes for production of Ga-68 and In-111 Octreoscan for same-day administration to Christie patients, using aseptic techniques

1.6 Packaging and dispatch of QC products to other hospitals, including liaison with drivers

1.7 Decontamination and cleaning of the Radiopharmacy post production, including tidying of waste and restocking of consumables

1.8 Packaging and return of used radionuclide generators to manufacturers

1.9 Production of the documentation for all the above processes (in compliance with GMP and data integrity principles)

1.10 Proposes changes to policies and procedures

1.11 Acts as in-process checking technician for the Radiopharmacy routine service and maintain this practice in accordance with local policy

2. Quality control

Carries out the programme of quality control of radiopharmaceuticals produced within the Regional Radiopharmacy, in compliance with the requirements of the Medicines Act. This includes:

2.1 Analysis of radiochemical purity using chromatography techniques

(ITLC and HPLC)

2.2 pH testing

2.3 Radionuclidic purity testing

2.4 Analysis of endotoxin levels

2.5 Ensuring that working areas are cleared after each operation

3. Environmental and microbiological monitoring

Participates in the programme of environmental and microbiological monitoring of the Radiopharmacy and blood labelling suites, to include:

3.1 Air quality and air flows

3.2 Microbiological contamination

3.3 Periodic monitoring of aseptic compliance for each member of staff

3.4 Integrity of air seals in the blood labelling suite

4. Regional blood cell labelling service

In the absence of the Senior Radiopharmaceutical Technologist, to be responsible on a day to day basis for the operation of the Regional blood cell labelling service, including:

4.1 Aseptic preparation of radio-labelled red and white blood cells, in multi-stage patient-critical procedures, prior to re-injection of the cells into patients for diagnostic scanning purposes

4.2 Liaison with customer departments for scheduling, transportation of blood to and from the customer department, and other arrangements

5. Management, supervision and training of staff

5.1 Deputises for the Senior Radiopharmaceutical Technologist in their absence.

5.2 Assists in the training of new staff and supervises the work of more junior members of the department

6. Stock control

Responsible for stock control and ordering of pharmaceutical products, including:

6.1 Pharmaceutical products, chemical reagents, and disposable items used in the radiopharmacy and associated areas

6.2 Consumable items for the Clinical Isotopes Department

6.3 Orders stock items for Radiopharmacy and Clinical Isotopes from Pharmacy

7. Training

7.1 Assists in the training of junior Radiopharmacy staff

7.2 Introduces pre-registration pharmacists and radiography students to Radiopharmacy.

8. Radiation protection

8.1 Monitors the radiopharmacy for radioactive contamination, and records results

8.2 Assesses requirement for decontamination procedures, and carries these out if necessary

9. Professional

9.1 Where applicable maintain GPhC Registration, for which participation in a continuous professional development programme is compulsory

9.2 Participate in an Annual Personal Development Review (PDR)

9.3 Demonstrates the agreed set of values and accountable for own attitude and behaviour


This advert closes on Thursday 3 Jul 2025

Proud member of the Disability Confident employer scheme

About Disability Confident

A Disability Confident employer will generally offer an interview to any applicant that declares they have a disability and meets the minimum criteria for the job as defined by the employer. It is important to note that in certain recruitment situations such as high-volume, seasonal and high-peak times, the employer may wish to limit the overall numbers of interviews offered to both disabled people and non-disabled people. For more details please go to Disability Confident.