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Clinical Scientist

Job details
Posting date: 24 March 2025
Salary: £46,148.00 to £52,809.00 per year
Additional salary information: £46148.00 - £52809.00 a year
Hours: Full time
Closing date: 07 April 2025
Location: Oxford, OX3 7LE
Company: NHS Jobs
Job type: Permanent
Job reference: C9321-25-0280

Summary

Clinical/Scientific1) Deliver the clinical service of a section/subsection of the laboratory or designated area of work to nationally accepted standards (CPA/UKAS or equivalent) with appropriate technical support to include the following:a. Undertake or supervise the receipt, processing and analysis of samples;and the checking, interpretation and reporting of results (both standardand complex).b. Access relevant sources of information to aid interpretation of patientresults, including critical appraisal of the information.c. Collate patient and clinical information to assist and support future patient management.d. Interpret results with advice on further action for patient or familymembers, including calculation of risk where appropriate, within relevantprofessional guidelines.2) Undertake appropriate complex or specialist technical and analytical procedures, as required, to process cells from a variety of biological specimens received which may be high risk (e.g. HIV, Hep C) and/ or derived from recognisable human or fetal parts. Work safely under exposure to toxic substances that are hazardous to health (e.g. PHA, colchicine)3) Undertake extended periods of analysis to identify genomic variation either through analysis of large data sets or examination of cytogenetic preparations4) Independently check and validate the analysis findings of other registered scientists, non-registered scientists and genetic technologists, authorising repeat analyses or subsequent investigations in accordance with laboratory protocols.Identify unusual results and bring them to the attention of senior scientists for further discussion5) Interpret findings from the range of investigations undertaken on a patient.Undertake detailed literature review and interrogation of databases to investigate the clinical significance of genomic variation detected. Prepare reports with clinical interpretation for final authorisation by Senior Registered Clinical Scientists/Principal Scientists/Consultant Scientists6) To authorise specified reports within their area of expertise where deemed competent by the Head of Laboratory under the direction of the Head of Section7) Act in an advisory capacity to clinical colleagues on the submission of samples,appropriate tests and in the interpretation of results in designated areas of the service8) Under the guidance of the Head of Service, attend appropriate multidisciplinary team meetings on behalf of the service to give professional opinion on clinical cases9) Supply a high level of scientific skill and expertise in the investigative procedures involved and take a high level of responsibility for his/her own work, with limited supervision from senior personnel in the laboratory. Be adaptable to changing diagnostic workload pressures, by making independent day-to-day decisions about own workload (e.g. prioritising own diagnostic cases or deciding when to undertake additional investigations). The post holder must communicate with,and when necessary obtain help/advice from, appropriate senior staff10)Maintain up to date specialist level knowledge of current scientific literature and information (e.g. Professional Best Practice) for defined services in order to ensure that the designated services are of high quality11)Maintain proficiency in the use of complex software for the analysis of genomic samples12)Maintain proficiency in the navigation, interrogation and application of all relevant and up to date genome browsers/information databases (e.g. DGV, DECIPHER, Exome Variant Server and Alamut Visual) to assess significance of copy number variants and/or identified mutations and maintain up to date knowledge of scientific and clinical advances in the field.