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Research Assistant - In Vitro Toxicology
| Posting date: | 28 June 2024 |
|---|---|
| Salary: | £32,982 to £37,099 per year |
| Hours: | Full time |
| Closing date: | 21 July 2024 |
| Location: | Swansea, Wales |
| Remote working: | On-site only |
| Company: | Swansea University |
| Job type: | Contract |
| Job reference: | SU00380 |
Summary
This is a Fixed Term position until August 2025, working full-time.
Titanium Dioxide is an industrially important material. There is concern that this material may induce DNA damage, but the scientific literature in this area is highly conflicting. Furthermore, positive findings are often associated with high cytotoxicity, oxidative stress, inflammation, apoptosis, necrosis, or combinations of these, indicating DNA damage if induced, may be secondary due to physiological stress. The research project that this role will focus upon will therefore be aimed at comprehensively evaluating a wide range of Titanium Dioxide forms to understand the underlying material characteristics that may be associated with inducing DNA damage and the molecular mechanisms involved, including the potential role of secondary genotoxicity.
The role may include national and European travel to attend and present at project meetings and conferences.
The person recruited to this post will hold an undergraduate degree in life-sciences or a related subject, with experience in laboratory-based research, data analysis / interpretation and reporting. It is desirable (but not essential) if you already possess a postgraduate degree in a relevant field or be near completion. Cell culture experience will be expected, and it will be beneficial if the appointee has experience of molecular biology techniques. Other skills that will be beneficial include knowledge in the areas of toxicology, cell and molecular biology and/or nanosafety.
Titanium Dioxide is an industrially important material. There is concern that this material may induce DNA damage, but the scientific literature in this area is highly conflicting. Furthermore, positive findings are often associated with high cytotoxicity, oxidative stress, inflammation, apoptosis, necrosis, or combinations of these, indicating DNA damage if induced, may be secondary due to physiological stress. The research project that this role will focus upon will therefore be aimed at comprehensively evaluating a wide range of Titanium Dioxide forms to understand the underlying material characteristics that may be associated with inducing DNA damage and the molecular mechanisms involved, including the potential role of secondary genotoxicity.
The role may include national and European travel to attend and present at project meetings and conferences.
The person recruited to this post will hold an undergraduate degree in life-sciences or a related subject, with experience in laboratory-based research, data analysis / interpretation and reporting. It is desirable (but not essential) if you already possess a postgraduate degree in a relevant field or be near completion. Cell culture experience will be expected, and it will be beneficial if the appointee has experience of molecular biology techniques. Other skills that will be beneficial include knowledge in the areas of toxicology, cell and molecular biology and/or nanosafety.