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Clinical Research Fellow | Royal Free London NHS Foundation Trust

Job details
Posting date: 08 April 2024
Salary: Not specified
Additional salary information: £43,923 - £55,329 Per annum plus London weighting
Hours: Full time
Closing date: 08 May 2024
Location: London, NW3 2QG
Company: Royal Free London NHS Foundation Trust
Job type: Contract
Job reference: 6012572/391-RFL-6012572

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Summary


Duties and Responsibilities

Applications are invited for a Clinical Research Fellow position. You will be based at the UCL Movement Disorders Centre, spanning UCL and the Royal Free and UCLH sites. You will develop and execute a research project in Parkinson’s disease and movement disorders genetics, under the supervision of Prof Huw Morris. The project will be based in part at the Department of Clinical and Movement Neuroscience, UCL. The project will include training in neurogenetics, gene / variant discovery and validation and in clinical trials based on genetic targets - focussed on Mendelian (single gene) disorders. The successful applicant will be expected to register for a PHD in a clinically based research project. The applicant will attend specialist clinics in movement disorders, paediatric movement disorders and neurogenetics and develop a lab based program of research. Further research aspects of the study may include development of cell models and the development of clinical trials related to genetic targets. This project will involve the analysis of large datasets through the GP2 project (https://gp2.org) based on large clinical cohorts established in the UK.

Key Requirements

Applicants should have be medically qualified and intend to pursue a career in Neurology and have a keen interest in Neurogenetics / Clinical Neuroscience. Experience in research and data analysis is desirable.



JOB SUMMARY: As a Clinical Research Fellow will be based at the UCL Movement Disorders Centre, spanning the Royal Free and UCLH sites. You will develop and execute a research project in Parkinson’s disease and movement disorders genetics, under the supervision of Prof Huw Morris. The project will be based in part at the Department of Clinical and Movement Neuroscience, UCL. The project will include training in neurogenetics, gene / variant discovery and validation and in clinical trials based on genetic targets - focussed on Mendelian (single gene) disorders. The successful applicant will be expected to register for a PHD in a clinically based research project. The applicant will attend specialist clinics in movement disorders, paediatric movement disorders and neurogenetics and develop a lab based program of research. Further research aspects of the study may include development of cell models and the development of clinical trials related to genetic targets. This project will involve the analysis of large datasets through the GP2 project (https://gp2.org) based on large clinical cohorts established in the UK.

Royal Free London NHS Foundation Trust

The Royal Free London NHS Foundation Trust runs three hospitals in London: Barnet Hospital, Chase Farm Hospital Royal Free Hospital

Across our three London hospitals, our vision is clear: to deliver world class expertise and local care.

We combine globally recognized clinical expertise with local and friendly hospital care to represent the NHS at its best.

Our mission is to be world class in terms of healthcare treatment, clinical research and teaching excellence. We aim to deliver and develop leading local healthcare in all three of our hospitals, to improve lives and help people thrive.



How the Royal Free will achieve its mission:

We will achieve our mission by making sure that we have:
• Excellent outcomes, in our clinical treatment, research and teaching
• Excellent experiences for patients, staff and GPs
• Excellent value, by improving the efficiency and productivity of our services, and reducing costs.
• Full compliance, meeting or exceeding all regulatory standards and outcomes we are set
• A strong organisation, investing effectively in our staff and infrastructure to make sure we are fit for future challenges



How the Royal Free measures its performance

In order to meet our aims, we want to ensure that our three London hospitals are in the top 10% of all healthcare providers for:
• quality of clinics and treatments
• medical research
• teaching and training new medical staff
• patient satisfaction and experience
• value for money





MAIN DUTIES AND RESPONSIBILITIES:

Duties of the Clinical Research Fellow post holder

The main duties of the post holder are to develop a research project related to the improved understanding and treatment of Parkinson’s disease and related conditions through neurogenetics.

This research fellowship was set up based on a bequest from Dr Janet Owens, a Royal Free alumnus.



The primary role of the appointee will be



Investigation of the genetic basis of Parkinson’s disease and related Movement Disorders



In addition
• Carry out clinical study assessments
• Prepare reports of study progress
• Deliver poster and oral presentations at National and International meetings
• Carry out and publish systematic reviews relating to aspects of Parkinson’s and movement disorders genetics
• Develop clinical skills in movement disorders, taking advantage of the teaching and learning opportunities at the UCL Movement Disorders Centre
• Develop one or more research projects depending on the interests and skills of the successful applicant
• Across the centre, we can support further research based on: clinical trial, disease biomarkers, cell models, pharmacogenomics.


Development opportunities

There are extensive opportunities for personal development in the Neurology departments of the Royal Free Hospital, National Hospital for Neurology and UCL Movement Disorders Centre. It is anticipated that the successful candidate would either already hold a National Training Number in Neurology or apply for an NTN in the final year of their appointment.

This job description outlines the current main responsibilities of the post. However the duties of the post may change and develop over time and may therefore be amended in consultation with the post holder,


This advert closes on Monday 29 Apr 2024

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