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Translation Research Scientist
| Posting date: | 25 March 2024 |
|---|---|
| Salary: | £44,350 per year |
| Hours: | Full time |
| Closing date: | 24 April 2024 |
| Location: | London, UK |
| Company: | The Francis Crick Institute |
| Job type: | Contract |
| Job reference: |
Summary
Translation Research Scientist
Short summary
We are looking to recruit an enthusiastic research scientist to this translational programme with strong expertise in biochemistry and molecular biology, interested in developing cutting-edge diagnostic technologies for cancer patients with DNA repair deficiencies. The successful candidate for this particular role will be embedded in the laboratory of Stephen West with a focus on cancer biology, investigating critical factors involved in DNA damage repair.
The goal of this project is to advance personalized medicine in oncology, ensuring that patients receive the most effective therapies based on their unique tumour profile, leading to improved patient outcomes and more efficient use of healthcare resources. Our approach is to develop a novel assay platform to assess DNA damage repair pathways. Our patent-pending technology has been supported by outstanding innovation-focused sponsors including the Crick Translation Fund, CRUK Cancer Research Horizons, MedTech SuperConnector, and Cancer Tech Accelerator.
Key Responsibilities
• Support the delivery of the project by undertaking laboratory research, developing the project in a timely and resource efficient manner (design and execute experiments, collect and analyse data)
• Lead on the optimization of cutting-edge assays to characterize DNA repair mechanisms in various biological models, playing a pivotal role in the assessment of clinical utility.
• Lead validation efforts to establish assay reliability and accuracy, comparing results with established benchmarks.
• Design and execute experiments for assay adaptation to scalable formats, contributing to the development of high-throughput capabilities.
• Develop and refine experimental protocols, ensuring the generation of high-quality data and compliance with industry and regulatory standards.
• Maintain electronic laboratory notebooks for proper documentation of research activities, ensuring data integrity and reproducibility.
• Participate in the research community by attending seminars, workshops, and conferences to stay abreast of the latest scientific advances and foster collaborative relationships.
Find out what benefits the Crick has to offer:
For more information on our great pay and benefits package please click here: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/pay-and-benefits
Equality, Diversity & Inclusion:
We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.
Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute’s success.
The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices.
Read more on our website: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/equality-diversity-and-inclusion
Short summary
We are looking to recruit an enthusiastic research scientist to this translational programme with strong expertise in biochemistry and molecular biology, interested in developing cutting-edge diagnostic technologies for cancer patients with DNA repair deficiencies. The successful candidate for this particular role will be embedded in the laboratory of Stephen West with a focus on cancer biology, investigating critical factors involved in DNA damage repair.
The goal of this project is to advance personalized medicine in oncology, ensuring that patients receive the most effective therapies based on their unique tumour profile, leading to improved patient outcomes and more efficient use of healthcare resources. Our approach is to develop a novel assay platform to assess DNA damage repair pathways. Our patent-pending technology has been supported by outstanding innovation-focused sponsors including the Crick Translation Fund, CRUK Cancer Research Horizons, MedTech SuperConnector, and Cancer Tech Accelerator.
Key Responsibilities
• Support the delivery of the project by undertaking laboratory research, developing the project in a timely and resource efficient manner (design and execute experiments, collect and analyse data)
• Lead on the optimization of cutting-edge assays to characterize DNA repair mechanisms in various biological models, playing a pivotal role in the assessment of clinical utility.
• Lead validation efforts to establish assay reliability and accuracy, comparing results with established benchmarks.
• Design and execute experiments for assay adaptation to scalable formats, contributing to the development of high-throughput capabilities.
• Develop and refine experimental protocols, ensuring the generation of high-quality data and compliance with industry and regulatory standards.
• Maintain electronic laboratory notebooks for proper documentation of research activities, ensuring data integrity and reproducibility.
• Participate in the research community by attending seminars, workshops, and conferences to stay abreast of the latest scientific advances and foster collaborative relationships.
Find out what benefits the Crick has to offer:
For more information on our great pay and benefits package please click here: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/pay-and-benefits
Equality, Diversity & Inclusion:
We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.
Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute’s success.
The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices.
Read more on our website: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/equality-diversity-and-inclusion