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Senior Scientist II – LC-MS/MS

Job details
Posting date: 22 May 2026
Hours: Full time
Closing date: 21 June 2026
Location: Macclesfield, Cheshire
Remote working: On-site only
Company: Synexa Life Sciences
Job type: Permanent
Job reference:

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Summary

Role Overview:
We are seeking a Senior Scientist II (Project Leader/Principal Investigator) – LC-MS/MS Bioanalysis (PK/PD)/Responsible Scientist to lead LC-MS/MS bioanalytical studies, ensuring scientific integrity, regulatory compliance, and successful study delivery.

Key Responsibilities:
Act as scientific lead for LC-MS/MS bioanalytical studies conducted under GLP and GCP. Oversee method development, validation, and sample analysis. Review and interpret analytical data to ensure quality and compliance. Lead investigations into analytical issues and implement corrective actions. Ensure studies meet regulatory requirements and internal standards. Act as primary scientific contact for clients. Prepare, review, and approve study documentation and reports.

Technical Expertise:
Strong experience in LC-MS/MS method development and validation. Understanding of sample preparation techniques and analytical workflows. Ability to troubleshoot issues such as matrix effects, sensitivity, and assay variability.

Qualifications and Experience:
MSc or PhD in Analytical Chemistry or related field. Five to ten or more years of LC-MS/MS bioanalysis experience. Experience leading regulated studies in a GLP/GCP environment.

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